From hot doctors on Grey's Anatomy to Shane's return, the upcoming fall TV season offers something for everyone. Eliza Dushku in leather pants? Check, Dollhouse. Jane Lynch as a bossy cheerleader coach? Check, Glee. Punky cute lesbians? Check, 90210. Bisexual publicists? Check, Melrose Place. There's sci-fi, drama, lesbians married to men and straight former cheerleaders getting chummy with their new college roommates and more to offer, starting this month as fall favorites and freshman series return to the airwaves as summer fades into the books. So sit back and check out SheWired's 10 to watch.

Grey's Anatomy

When we last left Seattle Grace, Callie (Sara Ramirez) and Arizona (Jessica Capshaw) experienced trouble in paradise as they disagreed over George (T.R. Knight) enlisting in the U.S. Army. While the hot docs are primetime's most visible lesbians now that Capshaw has been upped to series regular, let's hope ABC doesn't put their steamy story line on the back burner or give them the Dr. Hahn (Brooke Smith) treatment.

Grey's returns with a two-hour season premiere Thursday, Sept. 24 at 9 p.m. on ABC.

Three Rivers

Two words why you should look forward to this freshman medical drama: Kate Moennig. The former L Word star "straightens" up her hair and will play Dr. Miranda Foster, who according to CBS' tip sheet, is a surgical fellow with a "rebellious streak and fiery temper." The drama, which tells interwoven stories about organ transplants from the doctors', donors' and recipients' perspectives, also stars Moonlight's Alex O'Loughlin. Here's hoping Moennig's Shane roots come out quickly.

Three Rivers premieres Sunday, Oct. 4 at 9 p.m. on CBS.

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Glee

Created by the openly gay Ryan Murphy (Nip/Tuck), Glee's post-American Idol sneak preview in May was both a hit with critics and viewers, and why shouldn't it be? Jane Lynch plays a hilarious and ultra-competitive cheerleading coach in a show that revolves around the ailing high school glee club. The jock, nerd, social outcast, prima donna and hipster form one of the best ensemble casts on TV — and with musical soundtracks already planned, it's one of the most refreshing concepts on broadcast TV.

Glee premieres Wednesday, Sept. 9 at 9 p.m. on Fox.

Heroes

The cheerleader goes gay in college? That certainly seems to be the case as NBC's supernatural drama has cast Madeline Zima (the teen vixen from Showtime's Californiacation) to play invincible cheerleader Claire's(Hayden Panettiere) new college "roommate." Little is known about their relationship, but one thing is for sure: Zima will help Panettiere have a normal college experience. Let's hope Claire's love life is indestructible, too.

Heroes begins its fourth season Monday, Sept. 21 at 8 p.m. on NBC.

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90210

Rumer Willis, daughter of Bruce Willis and Demi Moore, has joined the hot ZIP code's second season and will guest star as a "punky cute lesbian who isn't afraid to speak her mind." Her character, Gia, will join West Beverly Hills High's student newspaper the Blaze, where she'll work with Adrianna (Jessica Lowndes) and Silver (Jessica Stroup). We hope Willis and Stroup make memorable headlines at school and at home!

90210 returns Tuesday, Sept. 8 at 8 p.m. on the CW.

Melrose Place

While you're already tuned in to the CW, why not stay for a while? With Katie Cassidy — yes, David Cassidy's daughter — set to play Ella, a bisexual publicist in the CW's remake of the 1990s hit, the CW will be creating love triangles in the Melrose Place apartment building before you can blink an eye. Co-starring Jessica Lucas (Cloverfield) and Laura Leighton as the infamous Sydney, there's no telling what's in store for the residents.

Melrose Place premieres Tuesday, Sept. 8 at 9 p.m. on the CW.

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Nip/Tuck

The "good" doctors return in October, only this time resident lesbian/anesthesiologist Liz (Roma Maffia) abandoned her Sapphic roots and tied the knot with Christian (Julian McMahon) after the two bonded while he "fought" cancer. Now that Kimber (Kelly Carlson) is looking for love — again — what will this mean for our Liz? Will she give Christian another verbal tongue-lashing or will Dr. Troy finally do the right thing? Ryan Murphy's envelope-pushing cosmetic surgery drama also will feature a roster of guest stars including Joan Rivers for its seventh and final season.

Nip/Tuck returns Oct. 14 at 10 p.m. on FX.

The Wanda Sykes Show

The new mom and co-star of CBS' The New Adventures of Old Christine is the latest in a long line of comedians to hit the late-night circuit. This time, Sykes hosts a Saturday night talk show focusing on topical issues, commentary and panel discussions with recurring participants. Regular field bits with the comedian will also be featured in the weekly hour.

Look for Sykes to fill your Saturday night calendar around November on Fox.

In the meantime, here's a look at Sykes with another of our favorite talk-show hosts:

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Dollhouse

Joss Whedon, creator of Buffy the Vampire Slayer, can write strong women. And joining Eliza Dushku (Echo) for a few episodes in Whedon's sci-fi Dollhouse this fall is Terminator: The Sarah Connor Chronicles' Summer Glau. With a cast already lined with Dichen Lachman (Sierra) and Amy Acker (Dr. Claire Saunders/Whiskey), as well as Dushku saying that the personality implant science fiction drama will focus on homosexuality as well as the "Dolls" regularly sharing the shower, let's hope the series avoids termination like it did last year.

Dollhouse returns for Season 2 on Friday, Sept. 25 at 9 p.m. on Fox.

The Big Bang Theory

Perhaps the cutest — and smartest — show on TV, The Big Bang Theory may not be swarming in LGBT story lines, but with Sara Gilbert recurring opposite former Rosanne co-star Johnny Galecki, this show has charm. Plus with hottie neighbor Kaley Cuoco and brainiac Jim Parsons, this is the underdog show that you should be watching. The boys are smart and humble, the women smart and sarcastic and the show provides a great alternative to Monday Night Football.

The Big Bang Theory returns Monday, Sept. 21 at 9:30 p.m. on CBS.

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