WATCH: Ellen DeGeneres Responds To Abercrombie's Sizeist CEO - 'Fitch, Please!'

America's favorite lesbian took on sizeist clothing store Abercrombie and Fitch on her daytime talk show Friday, weighing in on CEO Mike Jeffries' statement that his store won't carry sizes larger than a 10 for women, because Jeffries only wants "cool," "thin," "popular" kids wearing his overpriced polo shirts. 

DeGeneres addressed the controversy in her opening monologue, and as usual, hit the nail square on the head. 

"Beauty isn't between a size 0 and a size 8," said Cover Girl DeGeneres. "It is not a number at all. It is not physical. I mean, I know that when a certain someone became a Cover Girl, a lot of people were surprised. But now, everyone agrees that Sophia Vergara is beautiful."

Watch DeGeneres's brilliant takedown below.